Brigatinib is a highly potent and selective investigational ALK inhibitor with mean IC50 value ＜ 100 nM in Ba/F3 cells.
...Quality confirmed by NMR,HPLC & MS.
AVE 0991 sodium salt|AVE0991 sodium salt;AVE-0991 sodium salt|CAS 306288-04-0 Buy AVE 0991 sodium salt from supplier medchemexpress.com
AVE 0991 is a nonpeptide Ang-(1-7) receptor Mas agonist, represents an important step for exploration of the effects of Ang-(1-7) and testing of its potential as a cardiovascular drug.
THZ2|CAS 1604810-84-5 Buy THZ2 from supplier medchemexpress.com
THZ2 is a potent and selective CDK7 inhibitor with in vitro IC50 of 13.9 nM.
LY3023414|LY-3023414;LY 3023414|CAS 1386874-06-1 Buy LY3023414 from supplier medchemexpress.com
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK, extracted from patent WO/2012097039A1, compound example 1, has an IC50 of 64.9 nM, 42.1 nM, 10.6 nM, 19.1 nM for Akt1(pT308), Akt1 (pS473), P70S6(pT389), S6RP(pS240/242).
...Quality confirmed by NMR,HPLC & MS.
...Quality confirmed by NMR,HPLC & MS.
Exatecan|DX8951;DX 8951;DX-8951|CAS 171335-80-1 Buy Exatecan from supplier medchemexpress.com
Exatecan (DX-8951) is a totally synthetic analogue of the topoisomerase I-inhibitor camptothecin, which was synthesised to impart increased aqueous solubility, greater tumour efficacy, and less toxicity than camptothecin itself....Quality confirmed by NMR,HPLC & MS.
AN-2728|Crisaborole;AN2728;AN 2728|CAS 906673-24-3 Buy AN-2728 from supplier medchemexpress.com
AN-2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines. Quality confirmed by NMR,HPLC & MS.