GSK269962A(GSK269962) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively); displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases....Quality confirmed by NMR,HPLC & MS.
GSK269962A|GSK 269962A;GSK-269962A;GSK269962;GSK 269962;GSK-269962|CAS 850664-21-0 Buy GSK269962A from supplier medchemexpress.com
Otamixaban|FXV 673; FXV-673; FXV673|CAS 193153-04-7 Buy Otamixaban from supplier medchemexpress.com
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.
A-1155463|A1155463;A 1155463|CAS 1235034-55-5 Buy A-1155463 from supplier medchemexpress.com
A-1155463 is a highly potent and selective BCL-XL inhibitor, A-1155463 shows picomolar binding affinity to BCL-XL (Ki ＜0.01 nM), and >1000-fold weaker binding to BCL-2 (Ki = 80 nM) and related proteins BCL-W (Ki = 19 nM) and MCL-1 (Ki > 440 nM).
...Quality confirmed by NMR,HPLC & MS.
...Quality confirmed by NMR,HPLC & MS.
Danirixin|GSK1325756;GSK-1325756;GSK 1325756|CAS 954126-98-8 Buy Danirixin from supplier medchemexpress.com
Danirixin is a small molecule, non-peptide, high affinity (IC50 for CXCL8 binding = 12.5 nM), selective, and reversible CXCR2 antagonist.
...Quality confirmed by NMR,HPLC & MS.
...Quality confirmed by NMR,HPLC & MS.
RS 504393|RS-504393; RS504393|CAS 300816-15-3 Buy RS 504393 from supplier medchemexpress.com
RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively).
SB 525334|SB-525334; SB525334|CAS 356559-20-1 Buy SB 525334 from supplier medchemexpress.com
SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.